Hotels in Downtown South San Francisco

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Nov 24 - Nov 25
Tomorrow
Nov 25 - Nov 26
This weekend
Nov 28 - Nov 30
Next weekend
Dec 5 - Dec 7

Where to stay in Downtown South San Francisco?

Exterior
La Quinta Inn & Suites by Wyndham San Francisco Airport N

La Quinta Inn & Suites by Wyndham San Francisco Airport N

3.0 star property
Downtown South San Francisco
8.0 out of 10, Very Good, (2021)
$101 nightly
The price is $119
Dec 10 - Dec 11
Total with taxes and fees
La Quinta Inn & Suites by Wyndham San Francisco Airport N
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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When is the best time to visit Downtown South San Francisco?

Our prices for hotels in Downtown South San Francisco are cheapest in February
Price trends for hotels in Downtown South San Francisco
Pricing is based on two traveler single night rates
View properties in November
Currently viewing crowd sizes and weather for November.
Typical weather for South San Francisco
November
Low crowds
High 62°F / low 51°F. Sunny most days.
View properties in November
62°
weather_sun
November, Low crowds, average high temperature 62 degrees Fahrenheit, average low temperature 51 degrees Fahrenheit. Sunny most days.
51°
57°
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December, Low crowds, average high temperature 57 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
48°
58°
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January, Low crowds, average high temperature 58 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
48°
58°
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February, Low crowds, average high temperature 58 degrees Fahrenheit, average low temperature 48 degrees Fahrenheit. Sunny most days.
48°
58°
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March, Moderate crowds, average high temperature 58 degrees Fahrenheit, average low temperature 49 degrees Fahrenheit. Sunny most days.
49°
60°
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April, Moderate crowds, average high temperature 60 degrees Fahrenheit, average low temperature 50 degrees Fahrenheit. Sunny most days.
50°
62°
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May, High crowds, average high temperature 62 degrees Fahrenheit, average low temperature 52 degrees Fahrenheit. Sunny most days.
52°
65°
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June, Moderate crowds, average high temperature 65 degrees Fahrenheit, average low temperature 55 degrees Fahrenheit. Sunny most days.
55°
66°
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July, High crowds, average high temperature 66 degrees Fahrenheit, average low temperature 56 degrees Fahrenheit. Sunny most days.
56°
68°
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August, High crowds, average high temperature 68 degrees Fahrenheit, average low temperature 58 degrees Fahrenheit. Sunny most days.
58°
69°
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September, High crowds, average high temperature 69 degrees Fahrenheit, average low temperature 58 degrees Fahrenheit. Sunny most days.
58°
67°
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October, Moderate crowds, average high temperature 67 degrees Fahrenheit, average low temperature 56 degrees Fahrenheit. Sunny most days.
56°
Monthly weather averages (˚F)

Check out reviews of Downtown South San Francisco hotels guests love

Hilton San Francisco Financial District

Hilton San Francisco Financial District

10/10 Excellent
"Staff pleasant. No surprises. Solid Hotel with good location to get to many San Francisco areas."
Emile 3-night trip
Posted 2 days ago
Hilton San Francisco Financial District

Frequently asked questions

Is Downtown South San Francisco expensive to stay in?
You can find great hotels from $71 in Downtown South San Francisco to suit a range of budgets. If you're looking for an affordable stay in Downtown South San Francisco, La Quinta Inn & Suites by Wyndham San Francisco Airport N is a great low-cost option. To find the best low-cost hotel on Hotels.com that meets your needs, apply your search filters and then sort hotels by "Price: low to high".
How can I find discounted rates and deals for Downtown South San Francisco hotels?
Unlocking discounted rates at hotels in Downtown South San Francisco couldn't be simpler. Members save up to 20% on select hotels when signed in. Silver, Gold, and Platinum members can earn additional rewards on VIP Access bookings.
Can I receive a refund if I cancel my Downtown South San Francisco hotel booking?
The majority of hotels offer free cancellation, so you can receive a refund if you need to cancel your booking. Some Downtown South San Francisco hotels require you to cancel more than 24 hours before check-in, so look at your booking beforehand. For extra peace of mind before you book, filter hotels by "Property cancellation options" and select "Fully refundable property".
What are some of the best pet-friendly hotels in Downtown South San Francisco?
Traveling with your pet doesn't mean sacrificing a great hotel stay. In Downtown South San Francisco, our travelers love:
What are some of the best family hotels in Downtown South San Francisco?
If you're vacationing with your family, La Quinta Inn & Suites by Wyndham San Francisco Airport N is one of the best family hotels in Downtown South San Francisco. La Quinta Inn & Suites by Wyndham San Francisco Airport N has a great average guest score of 8 out of 10 and amenities like an outdoor pool, a free continental breakfast and in-room cribs. To explore more family hotels in Downtown South San Francisco, use the "Family friendly" filter in your search on Hotels.com.
What are some of the best Downtown South San Francisco hotels with a pool?
Book a Downtown South San Francisco hotel with a pool for some added relaxation or exercise on your trip. La Quinta Inn & Suites by Wyndham San Francisco Airport N is a top-rated hotel with an outdoor pool, and an average guest score of 8 out of 10. This hotel also features a free continental breakfast and a 24-hour gym. For more Downtown South San Francisco hotels with a pool, use the "Amenities" filter in your search and select "Pool" on Hotels.com.
Is it worth staying in Downtown South San Francisco?
There are 13 hotels in the area to find your perfect somewhere. Basing yourself in Downtown South San Francisco makes it easy to explore South San Francisco, including the neighborhoods of Colma and Bayview.
Are all taxes and fees included in the Downtown South San Francisco hotel prices shown on Hotels.com?
Hotels.com provides upfront pricing so you can relax knowing you won't be met with surprise additional fees or taxes when you're ready to confirm your booking. From the time you start your search on Hotels.com, the price you see is what you pay. This makes it much easier to compare properties and secure our best deal for your next getaway.
Find out more about Downtown South San Francisco

What's Downtown South San Francisco Like?

If you want to find the perfect part of the city to explore, why not check out Downtown South San Francisco? In the larger area, you'll find top places to visit like Moscone Convention Center. South San Francisco Convention Center and SFO Museum are two places to visit nearby.

How to Get to Downtown South San Francisco

Flying to:

  • San Francisco Intl. Airport (SFO), 3.2 mi (5.2 km) from Downtown South San Francisco
  • Oakland Intl. Airport (OAK), 11.8 mi (18.9 km) from Downtown South San Francisco
  • San Carlos, CA (SQL), 13.4 mi (21.5 km) from Downtown South San Francisco

Things to See and Do in and around Downtown South San Francisco

Things to See near Downtown South San Francisco:

  • South San Francisco Convention Center (0.9 mi/1.5 km away)
  • San Francisco Baking Institute (1.6 mi/2.6 km away)
  • Cow Palace (3.5 mi/5.6 km away)
  • Bayfront Park (4.2 mi/6.8 km away)
  • San Bruno Point Park (1.7 mi/2.7 km away)

Things to Do near Downtown South San Francisco:

  • SFO Museum (1.7 mi/2.8 km away)
  • Artichoke Joe's Casino (2 mi/3.2 km away)
  • Serramonte Center (3.2 mi/5.1 km away)
  • Millbrae Square Shopping Center (3.8 mi/6.1 km away)
  • See's Candies (1 mi/1.7 km away)

When Is the Best Time to Visit South San Francisco?

  • Hottest months: September, August, October, July (average 62°F)
  • Coldest months: February, January, December, March (average 53°F)
  • Rainiest months: December, January, February, March (average 4 inches of rainfall)

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